| November 18, 2000 | vs Miami (OH) | W 68-54 |
| November 22, 2000 | vs Eastern Kentucky | W 93-75 |
| November 28, 2000 | vs Samford | W 65-55 |
| November 30, 2000 | vs Louisiana-Monroe | W 86-68 |
| December 2, 2000 | vs Wisconsin Badgers | L 46-61 |
| December 5, 2000 | vs San Francisco | W 75-49 |
| December 9, 2000 | vs Princeton | L 52-58 |
| December 14, 2000 | vs Cincinnati Bearcats | W 69-67 |
| December 16, 2000 | vs Marquette Golden Eagles | W 75-59 |
| December 23, 2000 | vs Toledo | W 63-61 |
| December 30, 2000 | vs Kent State | W 71-60 |
| January 3, 2001 | vs Fordham | W 82-71 |
| January 7, 2001 | vs La Salle | W 81-66 |
| January 9, 2001 | vs UMass Minutemen | L 64-75 |
| January 13, 2001 | vs Rhode Island Rams | W 99-82 |
| January 16, 2001 | vs George Washington | W 76-74 |
| January 20, 2001 | vs Saint Joseph's | W 86-73 |
| January 27, 2001 | vs Duquesne | W 81-48 |
| January 30, 2001 | vs Dayton Flyers | W 82-72 |
| February 3, 2001 | vs George Washington | W 71-63 |
| February 7, 2001 | vs Saint Joseph's | L 76-79 |
| February 10, 2001 | vs Temple | W 78-71 |
| February 14, 2001 | vs UMass Minutemen | L 49-59 |
| February 17, 2001 | vs Rhode Island Rams | W 79-65 |
| February 21, 2001 | vs St. Bonaventure | W 77-60 |
| February 25, 2001 | vs La Salle | W 79-55 |
| March 4, 2001 | vs Dayton Flyers | L 62-65 |
| March 8, 2001 | vs George Washington | L 74-83 |
| March 16, 2001 | vs Notre Dame Fighting Irish | L 71-83 |
