| December 8, 1965 | vs Canisius | W 94-73 |
| December 11, 1965 | vs St. Bonaventure | L 72-92 |
| December 13, 1965 | vs Detroit Mercy | L 86-105 |
| December 18, 1965 | vs Fairfield | L 81-90 |
| December 20, 1965 | vs Citadel | W 104-81 |
| December 28, 1965 | vs Wichita State Shockers | L 81-82 |
| December 29, 1965 | vs Texas A&M Aggies | W 98-86 |
| December 30, 1965 | vs Wyoming | W 90-86 |
| January 3, 1966 | vs Dayton Flyers | L 79-105 |
| January 8, 1966 | vs Marquette Golden Eagles | L 64-103 |
| January 12, 1966 | vs Villanova Wildcats | L 82-90 |
| January 15, 1966 | vs Saint Francis (PA) | W 113-85 |
| January 24, 1966 | vs Detroit Mercy | L 87-95 |
| January 29, 1966 | vs Memphis Tigers | W 110-107 |
| January 31, 1966 | vs Loyola (LA) | W 76-74 |
| February 5, 1966 | vs Miami (OH) | L 68-76 |
| February 9, 1966 | vs Dayton Flyers | L 73-76 |
| February 11, 1966 | vs Kent State | W 85-76 |
| February 13, 1966 | vs Duquesne | W 79-75 |
| February 16, 1966 | vs Marquette Golden Eagles | W 82-78 |
| February 22, 1966 | vs Miami (OH) | L 72-76 |
| February 26, 1966 | vs Saint Joseph's | L 83-101 |
| March 3, 1966 | vs Cincinnati Bearcats | L 62-67 |
