| December 1, 1965 | vs Virginia Military Institute | W 69-58 |
| December 4, 1965 | vs George Washington | W 105-80 |
| December 8, 1965 | vs Virginia Military Institute | W 93-75 |
| December 11, 1965 | vs Illinois Fighting Illini | L 86-96 |
| December 14, 1965 | vs Richmond | W 95-85 |
| December 17, 1965 | vs Marquette Golden Eagles | L 87-100 |
| December 18, 1965 | vs Wisconsin Badgers | W 101-93 |
| December 21, 1965 | vs Maryland Terrapins | W 76-74 |
| December 30, 1965 | vs North Carolina State Wolfpack | L 77-94 |
| December 31, 1965 | vs North Carolina Tar Heels | W 102-97 |
| January 6, 1966 | vs New York University | L 91-104 |
| January 8, 1966 | vs Davidson Wildcats | L 79-105 |
| January 15, 1966 | vs Penn State Nittany Lions | W 73-64 |
| January 25, 1966 | vs Pittsburgh Panthers | W 90-79 |
| January 29, 1966 | vs Furman | W 85-81 |
| January 31, 1966 | vs St. John's (NY) | W 73-72 |
| February 2, 1966 | vs Davidson Wildcats | W 74-65 |
| February 5, 1966 | vs George Washington | W 90-79 |
| February 7, 1966 | vs Duke Blue Devils (3) | W 94-90 |
| February 11, 1966 | vs Richmond | L 82-84 |
| February 12, 1966 | vs Maryland Terrapins | L 92-107 |
| February 14, 1966 | vs Pittsburgh Panthers | W 103-63 |
| February 16, 1966 | vs Penn State Nittany Lions | L 81-108 |
| February 19, 1966 | vs Syracuse Orange | W 99-95 |
| February 24, 1966 | vs Virginia Military Institute | W 95-80 |
| February 25, 1966 | vs William & Mary | W 64-50 |
| February 26, 1966 | vs Davidson Wildcats | L 69-80 |
