| December 4, 1965 | vs Ole Miss Rebels | W 80-71 |
| December 6, 1965 | vs LSU Tigers | L 66-76 |
| December 13, 1965 | vs Oklahoma State Cowboys | W 56-51 |
| December 14, 1965 | vs Nebraska Cornhuskers | L 64-75 |
| December 20, 1965 | vs Memphis Tigers | W 80-72 |
| December 21, 1965 | vs Northwestern Wildcats | L 71-73 |
| December 29, 1965 | vs Seattle | L 80-95 |
| December 30, 1965 | vs California Golden Bears | L 77-82 |
| January 4, 1966 | vs Rice | W 94-85 |
| January 8, 1966 | vs Southern Methodist | L 78-99 |
| January 11, 1966 | vs Baylor Bears | L 74-89 |
| January 15, 1966 | vs Arkansas Razorbacks | L 82-93 |
| January 18, 1966 | vs Texas A&M Aggies | L 57-64 |
| February 5, 1966 | vs Texas Tech Red Raiders | W 87-74 |
| February 8, 1966 | vs TCU Horned Frogs | W 77-75 |
| February 12, 1966 | vs Texas A&M Aggies | W 110-82 |
| February 15, 1966 | vs TCU Horned Frogs | W 85-77 |
| February 19, 1966 | vs Texas Tech Red Raiders | L 86-117 |
| February 22, 1966 | vs Rice | W 91-82 |
| February 26, 1966 | vs Southern Methodist | L 69-71 |
| March 1, 1966 | vs Arkansas Razorbacks | W 74-70 |
| March 3, 1966 | vs Baylor Bears | L 71-88 |
