| December 4, 1965 | vs Furman | W 97-79 |
| December 6, 1965 | vs Duke Blue Devils | W 73-71 |
| December 11, 1965 | vs Pennsylvania | W 42-39 |
| December 16, 1965 | vs New York University | L 66-83 |
| January 3, 1966 | vs Clemson Tigers | W 57-48 |
| January 5, 1966 | vs North Carolina State Wolfpack | L 54-55 |
| January 12, 1966 | vs Furman | L 66-73 |
| January 15, 1966 | vs Clemson Tigers | L 82-86 |
| January 29, 1966 | vs Virginia Cavaliers | W 82-64 |
| January 31, 1966 | vs Maryland Terrapins | L 63-78 |
| February 5, 1966 | vs Wake Forest Demon Deacons | L 62-93 |
| February 7, 1966 | vs North Carolina Tar Heels (6) | L 70-104 |
| February 12, 1966 | vs Wake Forest Demon Deacons | L 63-65 |
| February 14, 1966 | vs Duke Blue Devils | L 38-41 |
| February 18, 1966 | vs North Carolina State Wolfpack | L 63-68 |
| February 19, 1966 | vs North Carolina Tar Heels | L 71-83 |
| February 25, 1966 | vs Maryland Terrapins | L 42-56 |
| February 26, 1966 | vs Virginia Cavaliers | W 59-57 |
| March 3, 1966 | vs Clemson Tigers | W 60-52 |
| March 4, 1966 | vs North Carolina State Wolfpack | L 62-75 |
