| November 6, 2018 | vs Youngstown State | W 69-53 |
| November 9, 2018 | vs Virginia Military Institute | W 94-55 |
| November 12, 2018 | vs Troy | W 84-75 |
| November 15, 2018 | vs Central Arkansas | W 97-71 |
| November 17, 2018 | vs North Alabama | W 71-66 |
| November 21, 2018 | vs Saint Louis | W 75-73 |
| November 27, 2018 | vs Iowa Hawkeyes (14) | L 68-69 |
| November 30, 2018 | vs Duquesne | W 74-53 |
| December 3, 2018 | vs Niagara | L 70-71 |
| December 8, 2018 | vs West Virginia Mountaineers | L 59-69 |
| December 15, 2018 | vs Maryland-Eastern Shore | W 78-43 |
| December 20, 2018 | vs New Orleans | W 99-57 |
| December 29, 2018 | vs Colgate | W 68-54 |
| January 5, 2019 | vs North Carolina Tar Heels (15) | L 60-85 |
| January 9, 2019 | vs Louisville Cardinals | W 89-86 |
| January 12, 2019 | vs North Carolina State Wolfpack (15) | L 80-86 |
| January 14, 2019 | vs Florida State Seminoles (11) | W 75-62 |
| January 19, 2019 | vs Syracuse Orange | L 63-74 |
| January 22, 2019 | vs Duke Blue Devils (2) | L 64-79 |
| January 26, 2019 | vs Louisville Cardinals (23) | L 51-66 |
| January 29, 2019 | vs Clemson Tigers | L 69-82 |
| February 2, 2019 | vs Syracuse Orange | L 56-65 |
| February 5, 2019 | vs Wake Forest Demon Deacons | L 76-78 |
| February 9, 2019 | vs North Carolina State Wolfpack | L 76-79 |
| February 12, 2019 | vs Boston College Eagles | L 57-66 |
| February 16, 2019 | vs Virginia Tech Hokies (22) | L 64-70 |
| February 20, 2019 | vs Georgia Tech Yellow Jackets | L 65-73 |
| February 27, 2019 | vs Clemson Tigers | L 48-62 |
| March 2, 2019 | vs Virginia Cavaliers (2) | L 49-73 |
| March 5, 2019 | vs Miami (FL) Hurricanes (6) | L 63-76 |
| March 9, 2019 | vs Notre Dame Fighting Irish | W 56-53 |
| March 12, 2019 | vs Boston College Eagles | W 80-70 |
| March 13, 2019 | vs Syracuse Orange | L 59-73 |
