| November 17, 2000 | vs Alcorn State | W 75-56 |
| November 18, 2000 | vs La Salle | W 89-72 |
| November 24, 2000 | vs Montana State | W 84-76 |
| November 25, 2000 | vs Tulane | W 83-69 |
| November 26, 2000 | vs Oregon State Beavers | W 78-60 |
| December 2, 2000 | vs Ole Miss Rebels | L 55-60 |
| December 9, 2000 | vs North Texas | W 100-72 |
| December 16, 2000 | vs Coppin State | W 103-49 |
| December 20, 2000 | vs Texas State | W 96-48 |
| December 23, 2000 | vs Arkansas Razorbacks | W 88-79 |
| December 29, 2000 | vs Oral Roberts | W 84-51 |
| December 30, 2000 | vs Southern Methodist | W 79-78 |
| January 6, 2001 | vs Iowa State Cyclones | L 80-100 |
| January 9, 2001 | vs Texas A&M Aggies | W 78-65 |
| January 13, 2001 | vs Kansas Jayhawks | L 61-69 |
| January 16, 2001 | vs Texas Tech Red Raiders | L 59-60 |
| January 20, 2001 | vs Kansas State Wildcats | W 64-63 |
| January 24, 2001 | vs Texas Longhorns | W 75-68 |
| January 27, 2001 | vs Nebraska Cornhuskers | W 77-66 |
| January 31, 2001 | vs Baylor Bears | W 65-51 |
| February 3, 2001 | vs Texas A&M Aggies | W 72-63 |
| February 7, 2001 | vs Texas Tech Red Raiders | W 80-72 |
| February 10, 2001 | vs Texas Longhorns | W 75-54 |
| February 14, 2001 | vs Oklahoma State Cowboys | L 44-72 |
| February 17, 2001 | vs Baylor Bears | W 82-60 |
| February 19, 2001 | vs Missouri Tigers | W 63-61 |
| February 24, 2001 | vs Maryland Terrapins | L 60-68 |
| February 28, 2001 | vs Colorado Buffaloes | W 86-67 |
| March 3, 2001 | vs Oklahoma State Cowboys | W 68-56 |
| March 9, 2001 | vs Missouri Tigers | W 67-65 |
| March 10, 2001 | vs Kansas Jayhawks | W 62-57 |
| March 11, 2001 | vs Texas Longhorns | W 54-45 |
| March 16, 2001 | vs Indiana State | L 68-70 |
