| December 1, 1965 | vs Tennessee Volunteers | W 71-63 |
| December 4, 1965 | vs Bowling Green State | W 108-70 |
| December 8, 1965 | vs Wichita State Shockers | L 94-100 |
| December 11, 1965 | vs San Francisco | W 96-78 |
| December 21, 1965 | vs Duke Blue Devils | L 93-100 |
| December 22, 1965 | vs Butler Bulldogs | L 64-79 |
| December 28, 1965 | vs Arizona State Sun Devils | L 87-89 |
| December 29, 1965 | vs Air Force | W 83-74 |
| December 30, 1965 | vs Washington State Cougars | W 93-81 |
| January 8, 1966 | vs Ohio State Buckeyes | W 83-78 |
| January 10, 1966 | vs Indiana Hoosiers | W 88-68 |
| January 15, 1966 | vs Northwestern Wildcats | W 93-86 |
| January 22, 1966 | vs Minnesota Golden Gophers | W 97-85 |
| January 29, 1966 | vs Wisconsin Badgers | W 69-67 |
| February 1, 1966 | vs Illinois Fighting Illini | L 93-99 |
| February 5, 1966 | vs Indiana Hoosiers | W 93-76 |
| February 12, 1966 | vs Wisconsin Badgers | W 120-102 |
| February 19, 1966 | vs Purdue Boilermakers | W 128-94 |
| February 21, 1966 | vs Iowa Hawkeyes | L 82-91 |
| February 26, 1966 | vs Purdue Boilermakers | W 105-85 |
| February 28, 1966 | vs Iowa Hawkeyes | W 103-88 |
| March 5, 1966 | vs Northwestern Wildcats | W 105-92 |
| March 7, 1966 | vs Michigan State Spartans | L 77-86 |
| March 11, 1966 | vs Western Kentucky | W 80-79 |
| March 12, 1966 | vs Kentucky Wildcats | L 77-84 |
