| November 9, 2022 | vs Bellarmine | L 66-67 |
| November 12, 2022 | vs Wright State | L 72-73 |
| November 15, 2022 | vs Appalachian State | L 60-61 |
| November 21, 2022 | vs Arkansas Razorbacks | L 54-80 |
| November 22, 2022 | vs Texas Tech Red Raiders | L 38-70 |
| November 23, 2022 | vs Cincinnati Bearcats | L 62-81 |
| November 29, 2022 | vs Maryland Terrapins | L 54-79 |
| December 4, 2022 | vs Miami (FL) Hurricanes | L 53-80 |
| December 10, 2022 | vs Florida State Seminoles | L 53-75 |
| December 14, 2022 | vs Western Kentucky | W 94-83 |
| December 17, 2022 | vs Florida A&M | W 61-55 |
| December 20, 2022 | vs Lipscomb | L 67-75 |
| December 22, 2022 | vs North Carolina State Wolfpack | L 64-76 |
| December 31, 2022 | vs Kentucky Wildcats | L 63-86 |
| January 3, 2023 | vs Syracuse Orange | |
| January 7, 2023 | vs Wake Forest Demon Deacons | |
| January 11, 2023 | vs Clemson Tigers | |
| January 14, 2023 | vs North Carolina Tar Heels | |
| January 18, 2023 | vs Pittsburgh Panthers | |
| January 25, 2023 | vs Boston College Eagles | |
| January 28, 2023 | vs Notre Dame Fighting Irish | |
| February 1, 2023 | vs Georgia Tech Yellow Jackets | |
| February 4, 2023 | vs Florida State Seminoles | |
| February 7, 2023 | vs Pittsburgh Panthers | |
| February 11, 2023 | vs Miami (FL) Hurricanes | |
| February 15, 2023 | vs Virginia Cavaliers (14) | |
| February 18, 2023 | vs Clemson Tigers | |
| February 20, 2023 | vs Duke Blue Devils | |
| February 25, 2023 | vs Georgia Tech Yellow Jackets | |
| February 28, 2023 | vs Virginia Tech Hokies | |
| March 4, 2023 | vs Virginia Cavaliers | |
