| November 8, 2018 | vs Nicholls State | W 85-72 |
| November 13, 2018 | vs Southern | W 104-54 |
| November 16, 2018 | vs Vermont | W 86-78 |
| November 21, 2018 | vs Tennessee Volunteers (5) | L 81-92 |
| November 23, 2018 | vs Marquette Golden Eagles | L 74-77 |
| November 27, 2018 | vs Michigan State Spartans (9) | W 82-78 |
| December 1, 2018 | vs Seton Hall | W 70-65 |
| December 1, 2018 | vs | W 70-65 |
| December 5, 2018 | vs Central Arkansas | W 86-41 |
| December 8, 2018 | vs Indiana Hoosiers | L 67-68 |
| December 12, 2018 | vs Lipscomb | W 72-68 |
| December 15, 2018 | vs Kent State | W 83-70 |
| December 21, 2018 | vs Robert Morris | W 73-59 |
| December 29, 2018 | vs Kentucky Wildcats (16) | L 58-71 |
| January 6, 2019 | vs Miami (FL) Hurricanes | W 90-73 |
| January 9, 2019 | vs Pittsburgh Panthers | L 86-89 |
| January 12, 2019 | vs North Carolina Tar Heels (12) | W 83-62 |
| January 16, 2019 | vs Boston College Eagles | W 80-70 |
| January 19, 2019 | vs Georgia Tech Yellow Jackets | W 79-51 |
| January 24, 2019 | vs North Carolina State Wolfpack (21) | W 84-77 |
| January 26, 2019 | vs Pittsburgh Panthers | W 66-51 |
| January 30, 2019 | vs Wake Forest Demon Deacons | W 82-54 |
| February 2, 2019 | vs North Carolina Tar Heels (9) | L 69-79 |
| February 4, 2019 | vs Virginia Tech Hokies (11) | W 72-64 |
| February 9, 2019 | vs Florida State Seminoles (22) | L 75-80 |
| February 12, 2019 | vs Duke Blue Devils (2) | L 69-71 |
| February 16, 2019 | vs Clemson Tigers | W 56-55 |
| February 20, 2019 | vs Syracuse Orange (8) | L 49-69 |
| February 23, 2019 | vs Virginia Cavaliers (3) | L 52-64 |
| February 27, 2019 | vs Boston College Eagles | L 59-66 |
| March 3, 2019 | vs Notre Dame Fighting Irish (21) | W 75-61 |
| March 9, 2019 | vs Virginia Cavaliers | L 68-73 |
| March 13, 2019 | vs Notre Dame Fighting Irish | W 75-53 |
| March 14, 2019 | vs North Carolina Tar Heels | L 70-83 |
| March 21, 2019 | vs Minnesota Golden Gophers | L 76-86 |
