| December 2, 1968 | vs Butler Bulldogs | W 105-66 |
| December 6, 1968 | vs Creighton Bluejays | W 69-66 |
| December 14, 1968 | vs Iowa State Cyclones | W 75-48 |
| December 17, 1968 | vs Ohio | W 95-82 |
| December 19, 1968 | vs Tulane Green Wave | W 105-71 |
| December 21, 1968 | vs Houston Cougars | W 97-84 |
| December 27, 1968 | vs Creighton Bluejays | W 90-77 |
| December 28, 1968 | vs Miami (FL) Hurricanes | W 86-76 |
| January 4, 1969 | vs Minnesota Golden Gophers | W 80-58 |
| January 7, 1969 | vs Purdue Boilermakers | L 84-98 |
| January 11, 1969 | vs Northwestern Wildcats | W 82-77 |
| January 25, 1969 | vs Notre Dame Fighting Irish | W 91-57 |
| January 28, 1969 | vs Ohio State Buckeyes | L 67-76 |
| February 1, 1969 | vs Wisconsin Badgers | W 86-73 |
| February 8, 1969 | vs Iowa Hawkeyes | W 98-69 |
| February 11, 1969 | vs Michigan Wolverines | L 87-92 |
| February 15, 1969 | vs Michigan State Spartans | L 70-75 |
| February 18, 1969 | vs Ohio State Buckeyes | W 73-57 |
| February 22, 1969 | vs Michigan Wolverines | W 100-92 |
| February 25, 1969 | vs Iowa Hawkeyes | L 53-74 |
| March 1, 1969 | vs Indiana Hoosiers | W 77-64 |
| March 4, 1969 | vs Michigan State Spartans | W 71-57 |
| March 8, 1969 | vs Northwestern Wildcats | W 78-68 |
