| December 4, 1964 | vs UCLA Bruins | W 110-83 |
| December 5, 1964 | vs Saint Louis | L 64-79 |
| December 8, 1964 | vs Bowling Green State | W 100-62 |
| December 15, 1964 | vs Wisconsin Badgers | W 70-56 |
| December 18, 1964 | vs Dayton Flyers | W 104-86 |
| December 19, 1964 | vs Kentucky Wildcats | W 91-86 |
| December 26, 1964 | vs New York University | W 102-79 |
| December 28, 1964 | vs Saint Joseph's | L 71-75 |
| December 29, 1964 | vs Villanova Wildcats | W 74-65 |
| January 4, 1965 | vs Indiana Hoosiers | W 86-81 |
| January 9, 1965 | vs Michigan Wolverines | L 83-89 |
| January 16, 1965 | vs Minnesota Golden Gophers | W 75-72 |
| January 30, 1965 | vs Notre Dame Fighting Irish | W 101-87 |
| February 6, 1965 | vs Purdue Boilermakers | W 121-93 |
| February 8, 1965 | vs Ohio State Buckeyes | W 86-71 |
| February 13, 1965 | vs Minnesota Golden Gophers | L 90-105 |
| February 16, 1965 | vs Ohio State Buckeyes | W 95-72 |
| February 20, 1965 | vs Michigan State Spartans | W 113-94 |
| February 23, 1965 | vs Iowa Hawkeyes | W 97-80 |
| February 27, 1965 | vs Michigan Wolverines | L 79-80 |
| March 2, 1965 | vs Northwestern Wildcats | W 93-70 |
| March 6, 1965 | vs Iowa Hawkeyes | L 84-94 |
| March 9, 1965 | vs Michigan State Spartans | W 121-89 |
