| November 12, 2010 | vs Southern | W 117-72 |
| November 14, 2010 | vs IUPUI | W 86-56 |
| November 16, 2010 | vs San Diego State Aztecs | L 76-79 |
| November 22, 2010 | vs Kansas State Wildcats (4) | L 64-81 |
| November 23, 2010 | vs Marquette Golden Eagles | W 66-63 |
| November 30, 2010 | vs Eastern Washington | W 86-57 |
| December 4, 2010 | vs Illinois Fighting Illini (20) | L 61-73 |
| December 8, 2010 | vs Washington State Cougars | L 59-81 |
| December 11, 2010 | vs Notre Dame Fighting Irish (23) | L 79-83 |
| December 18, 2010 | vs Baylor Bears (9) | W 68-64 |
| December 22, 2010 | vs Xavier Musketeers | W 64-54 |
| December 29, 2010 | vs Lafayette | W 83-55 |
| December 31, 2010 | vs Oklahoma State Cowboys | W 73-52 |
| January 2, 2011 | vs Wake Forest Demon Deacons | W 73-63 |
| January 8, 2011 | vs Portland | W 74-61 |
| January 13, 2011 | vs Pepperdine | W 92-75 |
| January 15, 2011 | vs Loyola Marymount | W 79-59 |
| January 20, 2011 | vs Santa Clara | L 71-85 |
| January 22, 2011 | vs San Francisco | L 91-96 |
| January 27, 2011 | vs Saint Mary's (CA) | L 71-73 |
| January 29, 2011 | vs San Diego | W 86-53 |
| February 3, 2011 | vs Portland | W 67-64 |
| February 5, 2011 | vs Memphis Tigers | L 58-62 |
| February 10, 2011 | vs Loyola Marymount | W 67-57 |
| February 12, 2011 | vs Pepperdine | W 63-44 |
| February 17, 2011 | vs Santa Clara | W 85-76 |
| February 19, 2011 | vs San Francisco | W 70-53 |
| February 24, 2011 | vs Saint Mary's (CA) | W 89-85 |
| February 26, 2011 | vs San Diego | W 68-31 |
| February 28, 2011 | vs Cal State Bakersfield | W 96-49 |
| March 6, 2011 | vs San Francisco | W 71-67 |
| March 7, 2011 | vs Saint Mary's (CA) | W 75-63 |
| March 17, 2011 | vs St. John's (NY) | W 86-71 |
| March 19, 2011 | vs BYU Cougars | L 67-89 |
