| November 8, 2022 | vs Coppin State | W 99-89 |
| November 12, 2022 | vs Green Bay | W 92-58 |
| November 15, 2022 | vs Northwestern Wildcats | L 63-75 |
| November 18, 2022 | vs Loyola Marymount | L 66-84 |
| November 20, 2022 | vs La Salle | W 69-62 |
| November 23, 2022 | vs American | L 70-74 |
| November 26, 2022 | vs Maryland-Baltimore County | W 79-70 |
| November 30, 2022 | vs Texas Tech Red Raiders | L 65-79 |
| December 3, 2022 | vs South Carolina Gamecocks | L 71-74 |
| December 7, 2022 | vs Siena | W 75-68 |
| December 10, 2022 | vs Syracuse Orange | L 64-83 |
| December 16, 2022 | vs Xavier Musketeers | L 89-102 |
| December 20, 2022 | vs Connecticut Huskies | L 73-84 |
| December 29, 2022 | vs DePaul Blue Demons | L 76-83 |
| January 1, 2023 | vs Butler Bulldogs | L 51-80 |
| January 4, 2023 | vs Villanova Wildcats | |
| January 7, 2023 | vs Marquette Golden Eagles | |
| January 10, 2023 | vs Seton Hall | |
| January 16, 2023 | vs Villanova Wildcats | |
| January 21, 2023 | vs Xavier Musketeers | |
| January 24, 2023 | vs DePaul Blue Demons | |
| January 29, 2023 | vs St. John's (NY) | |
| February 1, 2023 | vs Creighton Bluejays | |
| February 4, 2023 | vs Connecticut Huskies | |
| February 8, 2023 | vs Providence Friars | |
| February 11, 2023 | vs Marquette Golden Eagles | |
| February 14, 2023 | vs Seton Hall | |
| February 19, 2023 | vs Butler Bulldogs (24) | |
| February 22, 2023 | vs St. John's (NY) | |
| February 26, 2023 | vs Providence Friars | |
| March 1, 2023 | vs Creighton Bluejays | |
