| November 25, 2020 | vs Arizona State Sun Devils | |
| November 28, 2020 | vs Louisiana | W 112-82 |
| November 29, 2020 | vs Seton Hall Pirates | |
| November 29, 2020 | vs Washington Huskies | W 86-52 |
| December 2, 2020 | vs Illinois Fighting Illini | W 82-69 |
| December 5, 2020 | vs Gonzaga Bulldogs | |
| December 8, 2020 | vs Nicholls State | |
| December 9, 2020 | vs Stephen F. Austin | W 83-52 |
| December 13, 2020 | vs Texas Longhorns | |
| December 19, 2020 | vs Kansas State Wildcats | W 100-69 |
| December 21, 2020 | vs Arkansas-Pine Bluff | W 99-42 |
| December 29, 2020 | vs Central Arkansas | W 93-56 |
| December 30, 2020 | vs Alcorn State | W 105-76 |
| January 2, 2021 | vs Iowa State Cyclones | W 76-65 |
| January 6, 2021 | vs Oklahoma Sooners | W 76-61 |
| January 9, 2021 | vs TCU Horned Frogs | W 67-49 |
| January 12, 2021 | vs West Virginia Mountaineers | |
| January 16, 2021 | vs Texas Tech Red Raiders | W 68-60 |
| January 18, 2021 | vs Kansas Jayhawks | W 77-69 |
| January 23, 2021 | vs Oklahoma State Cowboys | W 81-66 |
| January 27, 2021 | vs Kansas State Wildcats | W 107-59 |
| January 30, 2021 | vs Auburn Tigers | W 84-72 |
| February 2, 2021 | vs Texas Longhorns | W 83-69 |
| February 6, 2021 | vs TCU Horned Frogs | |
| February 10, 2021 | vs Oklahoma Sooners (3) | |
| February 13, 2021 | vs Texas Tech Red Raiders | |
| February 15, 2021 | vs West Virginia Mountaineers | |
| February 18, 2021 | vs West Virginia Mountaineers | |
| February 20, 2021 | vs Oklahoma State Cowboys | |
| February 23, 2021 | vs Iowa State Cyclones | W 77-72 |
| February 25, 2021 | vs West Virginia Mountaineers | |
| February 27, 2021 | vs Kansas Jayhawks | |
| March 2, 2021 | vs West Virginia Mountaineers | |
| March 4, 2021 | vs Oklahoma State Cowboys | |
| March 7, 2021 | vs Texas Tech Red Raiders | |
