| November 22, 2000 | vs Arkansas-Pine Bluff | W 85-40 |
| December 2, 2000 | vs Little Rock | W 54-51 |
| December 16, 2000 | vs Cal State Fullerton | W 80-50 |
| December 19, 2000 | vs Grambling | W 91-82 |
| December 21, 2000 | vs Liberty | W 87-51 |
| December 23, 2000 | vs North Texas | W 88-63 |
| December 28, 2000 | vs Rice | W 73-57 |
| December 30, 2000 | vs Montana | W 77-57 |
| January 2, 2001 | vs Texas Southern | W 63-52 |
| January 6, 2001 | vs Colorado Buffaloes | W 61-56 |
| January 9, 2001 | vs Texas Tech Red Raiders | L 58-68 |
| January 13, 2001 | vs Kansas State Wildcats | W 63-55 |
| January 17, 2001 | vs Oklahoma State Cowboys | L 65-76 |
| January 20, 2001 | vs Texas Longhorns | L 66-73 |
| January 25, 2001 | vs Iowa State Cyclones | L 51-72 |
| January 31, 2001 | vs Oklahoma Sooners | L 51-65 |
| February 3, 2001 | vs Texas Tech Red Raiders | W 82-74 |
| February 6, 2001 | vs Texas A&M Aggies | L 69-73 |
| February 10, 2001 | vs Nebraska Cornhuskers | W 69-58 |
| February 12, 2001 | vs Kansas Jayhawks | W 85-77 |
| February 17, 2001 | vs Oklahoma Sooners | L 60-82 |
| February 21, 2001 | vs Texas Longhorns | L 59-69 |
| February 24, 2001 | vs Missouri Tigers | L 59-69 |
| February 28, 2001 | vs Oklahoma State Cowboys | L 68-71 |
| March 3, 2001 | vs Texas A&M Aggies | W 85-59 |
| March 8, 2001 | vs Colorado Buffaloes | W 86-84 |
| March 9, 2001 | vs Iowa State Cyclones | W 62-49 |
| March 10, 2001 | vs Texas Longhorns | L 62-76 |
| March 14, 2001 | vs New Mexico Lobos | L 73-83 |
